cytotoxic agents造句

• Combretastatin A-1 is also a potent cytotoxic agent.
• MMP inhibitors could also be administered along with cytotoxic agents or other proteinase inhibitors.
• Gemtuzumab is a monoclonal antibody to CD33 linked to a cytotoxic agent from the class of calicheamicins.
• The resulting complex  amino acid, linker and cytotoxic agent  now becomes the active drug.
• The sarcomeric effects of NRG-1 protects myocytes against structural disarray induced by stressors, including cytotoxic agents.
• It consists of an anti-CD19 mAb linked to monomethyl auristatin F ( MMAF ), a cytotoxic agent.
• Lymphocytopenia is a frequent, temporary result from many types of chemotherapy, such as with cytotoxic agents or immunosuppressive drugs.
• In areas of hypoxia, evofosfamide becomes activated and converts to an alkylating cytotoxic agent resulting in DNA cross-linking.
• It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F ( MMAF ), a cytotoxic agent.
• In contrast, " cleavable linkers " are catalyzed by enzymes in the cancer cell where it releases the cytotoxic agent.
• For platinum-sensitive tumors, platins are the drugs of choice for second-line chemotherapy, in combination with other cytotoxic agents.
• Intraperitoneal chemotherapy has also been under investigation during the 2000s and 2010s for its potential to deliver higher doses of cytotoxic agent to tumors.
• This pore consists of seven alpha-hemolysin subunits, which represent the major cytotoxic agent that is freed by this kind of bacterium.
• It was discovered that rapamycin had an anticancer activity and was a non-cytotoxic agent with cytostatic activity against several human cancer types.
• It used, often in combination with other cytotoxic agents, to treat various kinds of histiocytosis, including Erdheim Chester disease and Langerhans cell histiocytosis,
• Cytotoxic agents such as Cyclophosphamide and Methotrexate have been used in AIED treatment in the past, however findings have suggested limited symptom alleviation from these drugs.
• Under conditions of stress, including viral infection, cytotoxic agents, and oxidative stress, activation of NRG-1 / ErbB signaling can protect myocardial cells against apoptosis.
• "Preferentially killing rapidly replicating malignant cells via cytotoxic agents cause serious side effects by injuring normal cells, particularly hematopoeitic cells, intestinal cells, hair follicle and germ cells.
• "M . producens " is known for its toxicity, producing Lyngbyatoxin-a and other " antifungal and cytotoxic agents, including laxaphycin A and B and curacin A ."
• But in mammalian cells, there is only an indirect evidence linking ADPRase to a detoxifying role, and this comes from studies of the very specific rat liver ADPRibase-I by cytotoxic agents.